Precision Health and PGx Podcast

This podcast is all about the Pharmacist leveraging the power of Pharmacogenomics. PGX for Pharmacists is a member of the Pharmacy Podcast Network. Pharmacogenomics is the study of the role of the genome in drug response. Its name (pharmaco- + genomics) reflects its combining of pharmacology and genomics. Pharmacogenomics analyzes how the genetic makeup of an individual affects his/her response to drugs. It deals with the influence of acquired and inherited genetic variation on drug response in patients by correlating gene expression or single-nucleotide polymorphisms with pharmacokinetics (drug absorption, distribution, metabolism, and elimination) and pharmacodynamics (effects mediated through a drug’s biological targets).

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Episodes

Wednesday Jun 23, 2021

PART TWO: Pharmacogenomics Education is critical to advancing the Pharmacist's optimal impact on medication management as a tool to ensure the drugs prescribed work as intended. 
The State of the Industry -- Pharmacogenomics Education
Clinical pharmacogenomics activities may include designing patient-specific drug and dosage regimens based on genetic profile, documenting clinical recommendations, educating pharmacists and other health care professionals, and recommending testing
Advanced training in pharmacogenomics may open up more practice opportunities for pharmacists, such as developing clinical decision support tools in electronic health record systems that guide prescribers on appropriate drug therapy regimens based on genetic profiles. Additionally, pharmacists can develop institutional guidelines and processes for implementing clinical pharmacogenomics services into various practice settings.
Pharmacists can also develop patient education materials to explain the significance of the tests and serve as expert consultants in a pharmacogenomics service.
Special guest: David Hurley PhD. 
David Hurley grew up in Dunwoody, GA, then earned a BS in Biology and Physics from Guilford College in Greensboro, NC, in 1979. He received his PhD in Molecular and Cellular Biology from Penn State University in 1986. He joined the faculty in Cell and Molecular Biology at Tulane University in New Orleans in 1992. He developed "Cellular Biochemistry" as a senior-level course for premedical students, while maintaining a research focus on the regulation of gene transcription of the Growth Hormone gene in the pituitary. Dr Hurley was an National Science Foundation CAREER program awardee from 1996-2004, and was co-investigator on a National Institutes of Health grant for 17 years. After the devastation of Hurricane Katrina, he joined the Gatton School of Pharmacy at East Tennessee State University as an inaugural faculty member in July, 2007, as Professor and Vice-Chair in the Department of Pharmaceutical Sciences. He has 45 publications, is a member of The Endocrine Society, the Society for Neuroscience, the AACP, and has been a grant reviewer for 6 years with the National Institute for Diabetes, Digestive and Kidney Diseases.
Our host: Becky Winslow, PharmD 
Dr. Becky Winslow is a co-host on PGX for Pharmacists. She’s an accomplished Doctor of Clinical Pharmacy with more than twenty years of clinical pharmacotherapy and pharmacy business operations experience, which includes seven years of direct patient facing care, seven years of pharmacy management experience and six years of experience as a medical science liaison in the pharmacogenomics field. Becky Winslow excels at developing and managing collaborative relationships with healthcare professionals and key opinion leaders to stay abreast of emerging trends and to achieve project goals. Becky Winslow is an articulate communicator with extensive background in gathering and critically analyzing research and data; translating complex content into a level appropriate to the target audience; writing clinical and marketing content; presenting; teaching; and training.
This episode of the PGX for Pharmacist's podcast is brought to you by RxSafe. 
Thanks RxSafe for Sponsoring this episode: 
RxSafe.com 
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Friday Jun 04, 2021

Dr. Jai Patel, PharmD, BCOP, CPP Chair of Department of Cancer Pharmacology & Pharmacogenomics Dr. Jai Patel is a pharmacist who help create a pharmacogenomics fellowship which was not available at his school. He finished the Oncology/Pharmacogenomics Postdoctoral Fellowship at the UNC Eshelman School of Pharmacy. Dr. Patel: “I approached my mentor and said, ‘this is what I want to practice. I have the ambition and drive.’ I had to convince him I was a good investment. Just because something doesn’t exist, doesn’t mean it isn’t possible. That’s what will set you apart from others when trying to build something new. Health care is always changing. Position yourself to be in the forefront of medicine. Dr. Patel serves as Chair of the Department of Cancer Pharmacology and Pharmacogenomics at Levine Cancer Institute. He is also the associate Professor in the Division of Hematology/Oncology. Dr. Patel’s research focuses on translational and clinical pharmacogenomics and pharmacokinetics of anticancer therapies.  Behnaz Sarrami, MS, PharmD Pharmacogenomics (PGx) coach and consultant | MSL at Atheadx Behnaz Sarrami is the co-host to the PGx for Pharmacist Podcast. She is an expert in the field of PGx and mentor to pharmacist who are establishing their own PGx consulting business. She believes in personalizing a patient’s medication based on each individual’s genetic makeup and is keen in helping overcome barriers for both pharmacist and providers who want to implement PGx in any clinical setting. Behnaz received her Master’s degree in Biochemistry from Georgetown University and her Doctorate in Pharmacy from Creighton University. Behnaz has been a contributor of Washington University’s Public Health blog. She also serves as a consultant for a grant-funded research project which aims to increase medication adherence in older adults who suffer from mental health. This episode is sponsored by the Ultiguard Safe Pack. UltiGuard Safe Pack is the only pen needle product that comes with an all-in-one sharps container. Learn more about why UltiGuard Safe Pack is the best choice for your patients and your pharmacy.

Thursday May 27, 2021

Pharmacogenomics Education is critical to advancing the Pharmacist's optimal impact on medication management as a tool to ensure the drugs prescribed work as intended. 
The State of the Industry -- Pharmacogenomics Education
Clinical pharmacogenomics activities may include designing patient-specific drug and dosage regimens based on genetic profile, documenting clinical recommendations, educating pharmacists and other health care professionals, and recommending testing
Advanced training in pharmacogenomics may open up more practice opportunities for pharmacists, such as developing clinical decision support tools in electronic health record systems that guide prescribers on appropriate drug therapy regimens based on genetic profiles. Additionally, pharmacists can develop institutional guidelines and processes for implementing clinical pharmacogenomics services into various practice settings.
Pharmacists can also develop patient education materials to explain the significance of the tests and serve as expert consultants in a pharmacogenomics service.
Special guest: David Hurley PhD. 
David Hurley grew up in Dunwoody, GA, then earned a BS in Biology and Physics from Guilford College in Greensboro, NC, in 1979. He received his PhD in Molecular and Cellular Biology from Penn State University in 1986. He joined the faculty in Cell and Molecular Biology at Tulane University in New Orleans in 1992. He developed "Cellular Biochemistry" as a senior-level course for premedical students, while maintaining a research focus on the regulation of gene transcription of the Growth Hormone gene in the pituitary. Dr Hurley was an National Science Foundation CAREER program awardee from 1996-2004, and was co-investigator on a National Institutes of Health grant for 17 years. After the devastation of Hurricane Katrina, he joined the Gatton School of Pharmacy at East Tennessee State University as an inaugural faculty member in July, 2007, as Professor and Vice-Chair in the Department of Pharmaceutical Sciences. He has 45 publications, is a member of The Endocrine Society, the Society for Neuroscience, the AACP, and has been a grant reviewer for 6 years with the National Institute for Diabetes, Digestive and Kidney Diseases.
Our host: Becky Winslow, PharmD 
Dr. Becky Winslow is a co-host on PGX for Pharmacists. She’s an accomplished Doctor of Clinical Pharmacy with more than twenty years of clinical pharmacotherapy and pharmacy business operations experience, which includes seven years of direct patient facing care, seven years of pharmacy management experience and six years of experience as a medical science liaison in the pharmacogenomics field. Becky Winslow excels at developing and managing collaborative relationships with healthcare professionals and key opinion leaders to stay abreast of emerging trends and to achieve project goals. Becky Winslow is an articulate communicator with extensive background in gathering and critically analyzing research and data; translating complex content into a level appropriate to the target audience; writing clinical and marketing content; presenting; teaching; and training.
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Wednesday Apr 07, 2021

Behnaz Sarrami, MS, PharmD, a PGx for pharmacists podcast, joins Cari Lalande, PharmD where we discuss the clinical value and utility of PGx and how it can be implemented in a clinical setting. 

Friday Apr 02, 2021

Behnaz Sarrami, MS, PharmD, a PGx for pharmacists podcast, Maci Koesterer, PharmD candidate 2021 from St. Louis College of Pharmacy where we discuss her first virtual and unique rotation in PGx and her recommendations to other students.

Thursday Apr 01, 2021

Behnaz Sarrami, MS, PharmD, an entrepreneur and a coach in PGx who has started her own consulting business bringing awareness to the clinical value and utility of PGx to providers, pharmacists, and consumers.

Thursday Mar 18, 2021

Kristine Ashcraft, BS, MBA is a molecular biologist by training and is the former CEO and founder of YouScript, recently acquired by Invitae. She has worked in pharmacogenomics since 2000 and was recently named one of the 25 leading voices in precision medicine. Kristine has authored multiple publications on the clinical and economic benefits of pharmacogenomic testing including one lauded as one of the most  influential publications at an American Medical Informatics Association meeting.
Kristine has been interviewed by numerous media outlets including the New York Times, the Wall Street Journal, and NBC Nightly News and has spoken at SXSW, American Society of Human Genetics, and numerous precision medicine conferences. She is committed to catalyzing the adoption of precision medicine.
For all the PGX for Pharmacists episodes, please visit: PGX4RX.com 
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Monday Mar 08, 2021

Becky Winslow PharmD, of PGX for Pharmacists podcast, joins Eric Geyer PharmD in this mash-up 'Pharmacy Podcast' hybrid episode where we discuss not only the Plavix case but several other cases where pharmacogenomics could help make a huge difference in our healthcare system, including in how we treat opioid addiction.
Hawaii recently fined Bristol Myers Squibb and Sanofi under consumer protection standards for their drug Plavix (clopidogrel). This could be a game changing case due to the fact that it could have been prevented with more studies using pharmacogenomics. 
Special insert from KHON2 News with Hawaii Attorney General Clare Connors held a news conference on Tuesday to discuss the million-dollar lawsuit against Bristol-Myers Squibb Co. and Sanofi.
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Monday Jan 11, 2021

Becky Winslow, PharmD & Pharmacy Student Kaitlyn Marshall re-launch the PGX for Pharmacists. 
23andMe announced in August of 2020 that it has received a 510(k) clearance from the FDA that allows its direct-to-consumer personal pharmacogenetics report to guide use of two treatments without the need for confirmatory testing.
This action updates a De Novo approval granted to the consumer genomics company in late 2018. That decision allowed 23andMe to market a test for one of 33 variants across multiple genes that could impact metabolization of certain medication, but came with a handful of "special controls." Among these were labeling requirements that warned consumers not to use the product for any medication decisions without additional independent testing.
Guests: 
Becky Winslow, BS, PharmD - Medical Affairs 
Dr. Becky Winslow, earned both her Bachelors of Science in Biology and her doctorate in clinical pharmacy from Campbell University. She earned her Test2Learn(TM) Community-Based Pharmacogenomics Certificate, as well as, her  "Train the Trainer"  certification through NACDS and The University of Pittsburgh School of Pharmacy. 
Dr. Winslow brings over 20 years experience building clinical pharmacy programs, as well as, directing pharmacy business operations in the community setting to inGENEiosu RX. She has patient facing clinical experience as a pharmacist in retail, hospital, public health, and long term care pharmacies. Dr. Winslow founded and has owned her general pharmacy consulting business for over 20 years. In the last 6 years, she has specialized in pharmacogenomics consulting. 
Dr. Winslow's professional associations include being a member of the Clinical Pharmacogenetics Implementation Consortium and The Get the Medications Right Institute.
Now recognized as a community pharmacogenomics subject matter expert, Dr. Winslow is sought after to create and present original pharmacogenomics content and to consult for pharmacogenomics industry vendors and the clients they serve.
Kaitlyn Marshall - PharmD Candidate 2021
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Sunday Feb 03, 2019

Dr Sanjeda Chumki, PharmD talks with Ken Sternfeld, host of PGX for Pharmacists about Admera Health and the power of pharmacogenomics in the hands of the clinical pharmacist.
About Admera Health:
Admera Health is an advanced molecular diagnostics company focused on personalized medicine, non-invasive cancer testing and digital health.
Dedicated to developing cutting-edge diagnostics that span the continuum of care, Admera Health fulfills unmet medical needs with cost-effective tests and accurate analysis to guide patient care. Utilizing next generation technology platforms and advanced bioinformatics, Admera Health seeks to redefine disease screening, diagnosis, treatment, monitoring, and management through its innovative, personalized solutions.
It is our mission to deliver transformative, valuable solutions for patients, physicians, and clinical researchers. We are committed to improving the health and well-being of our global community through the direct delivery of personalized, medically actionable results.
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